La Santísima Flor de Lúpulo is an independent nano-brewery based in Oaxaca de Juárez, Mexico, founded by a diverse group of brewers united by a shared devotion to well-crafted beer. What began as a homebrewing project in 2012 evolved into a small but passionate operation dedicated to producing fresh, characterful beers using quality grains and seasonal hops. Rooted in experimentation and a deep appreciation for fermentation, the brewery serves its beers from a taproom in Oaxaca’s historic center while also reaching restaurants and craft beer enthusiasts throughout the region. In a city better known for mezcal, La Santísima Flor de Lúpulo represents Oaxaca’s growing and distinctive craft beer spirit.